000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Consolidated Balance Sheets link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Consolidated Balance Sheets (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Consolidated Statements of Operations and Comprehensive Loss link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Consolidated Statements of Stockholders' Deficit link:calculationLink link:definitionLink link:presentationLink 005 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 995552 - Disclosure - Note 1 - Nature of the Business link:calculationLink link:definitionLink link:presentationLink 995553 - Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 995554 - Disclosure - Note 3 - Cash and Cash Equivalents link:calculationLink link:definitionLink link:presentationLink 995555 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets link:calculationLink link:definitionLink link:presentationLink 995556 - Disclosure - Note 5 - Property and Equipment, Net link:calculationLink link:definitionLink link:presentationLink 995557 - Disclosure - Note 6 - Accrued Liabilities link:calculationLink link:definitionLink link:presentationLink 995558 - Disclosure - Note 7 - Leases link:calculationLink link:definitionLink link:presentationLink 995559 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable link:calculationLink link:definitionLink link:presentationLink 995560 - Disclosure - Note 9 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 995561 - Disclosure - Note 10 - Income Taxes link:calculationLink link:definitionLink link:presentationLink 995562 - Disclosure - Note 11 - Benefit Plans link:calculationLink link:definitionLink link:presentationLink 995563 - Disclosure - Note 12 - Fair Value link:calculationLink link:definitionLink link:presentationLink 995564 - Disclosure - Note 13 - Capital Stock link:calculationLink link:definitionLink link:presentationLink 995565 - Disclosure - Note 14 - Net Loss Per Share link:calculationLink link:definitionLink link:presentationLink 995566 - Disclosure - Note 15 - Related Party Transactions link:calculationLink link:definitionLink link:presentationLink 995567 - Disclosure - Note 16 - Geographic and Segment Information link:calculationLink link:definitionLink link:presentationLink 995568 - Disclosure - Note 17 - Subsequent Events link:calculationLink link:definitionLink link:presentationLink 995572 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 995573 - Disclosure - Note 3 - Cash and Cash Equivalents (Tables) link:calculationLink link:definitionLink link:presentationLink 995574 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets (Tables) link:calculationLink link:definitionLink link:presentationLink 995575 - Disclosure - Note 5 - Property and Equipment, Net (Tables) link:calculationLink link:definitionLink link:presentationLink 995576 - Disclosure - Note 6 - Accrued Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 995577 - Disclosure - Note 7 - Leases (Tables) link:calculationLink link:definitionLink link:presentationLink 995578 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable (Tables) link:calculationLink link:definitionLink link:presentationLink 995579 - Disclosure - Note 10 - Income Taxes (Tables) link:calculationLink link:definitionLink link:presentationLink 995580 - Disclosure - Note 11 - Benefit Plans (Tables) link:calculationLink link:definitionLink link:presentationLink 995581 - Disclosure - Note 12 - Fair Value (Tables) link:calculationLink link:definitionLink link:presentationLink 995582 - Disclosure - Note 13 - Capital Stock (Tables) link:calculationLink link:definitionLink link:presentationLink 995583 - Disclosure - Note 14 - Net Loss Per Share (Tables) link:calculationLink link:definitionLink link:presentationLink 995584 - Disclosure - Note 15 - Related Party Transactions (Tables) link:calculationLink link:definitionLink link:presentationLink 995585 - Disclosure - Note 16 - Geographic and Segment Information (Tables) link:calculationLink link:definitionLink link:presentationLink 995586 - Disclosure - Note 1 - Nature of the Business (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995587 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995588 - Disclosure - Note 3 - Cash and Cash Equivalents - Available-for-sale Securities (Details) link:calculationLink link:definitionLink link:presentationLink 995589 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Details) link:calculationLink link:definitionLink link:presentationLink 995590 - Disclosure - Note 5 - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details) link:calculationLink link:definitionLink link:presentationLink 995591 - Disclosure - Note 5 - Property and Equipment, Net - Schedule of Depreciation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995592 - Disclosure - Note 6 - Accrued Liabilities - Schedule of Accrued Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995593 - Disclosure - Note 7 - Leases (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995594 - Disclosure - Note 7 - Leases - Maturity Analysis of Leases (Details) link:calculationLink link:definitionLink link:presentationLink 995595 - Disclosure - Note 7 - Leases - Components of Lease Cost (Details) link:calculationLink link:definitionLink link:presentationLink 995596 - Disclosure - Note 7 - Leases - Supplemental Cash Flow Information (Details) link:calculationLink link:definitionLink link:presentationLink 995597 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995598 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Long-term Debt (Details) link:calculationLink link:definitionLink link:presentationLink 995599 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Interest Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995600 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Schedule of Future Payments (Details) link:calculationLink link:definitionLink link:presentationLink 995601 - Disclosure - Note 9 - Commitments and Contingencies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995602 - Disclosure - Note 10 - Income Taxes (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995603 - Disclosure - Note 10 - Income Taxes - Components of Income (Loss) Before Income Taxes (Details) link:calculationLink link:definitionLink link:presentationLink 995604 - Disclosure - Note 10 - Income Taxes - Reconciliation of Income Tax (Details) link:calculationLink link:definitionLink link:presentationLink 995605 - Disclosure - Note 10 - Income Taxes - Significant Components of Deferred Tax Assets (Liabilities) (Details) link:calculationLink link:definitionLink link:presentationLink 995606 - Disclosure - Note 11 - Benefit Plans (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995607 - Disclosure - Note 11 - Benefit Plans - Stock-based Compensation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995608 - Disclosure - Note 11 - Benefit Plans - Activity Related to Outstanding Stock Options (Details) link:calculationLink link:definitionLink link:presentationLink 995609 - Disclosure - Note 11 - Benefit Plans - Assumptions of Stock Options (Details) link:calculationLink link:definitionLink link:presentationLink 995610 - Disclosure - Note 11 - Benefit Plans - Activity Related to Restricted Stock Awards (Details) link:calculationLink link:definitionLink link:presentationLink 995611 - Disclosure - Note 12 - Fair Value (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995612 - Disclosure - Note 12 - Fair Value - Assets and Liabilities Measured on a Recurring Basis (Details) link:calculationLink link:definitionLink link:presentationLink 995613 - Disclosure - Note 12 - Fair Value - Unobservable Inputs (Details) link:calculationLink link:definitionLink link:presentationLink 995614 - Disclosure - Note 13 - Capital Stock (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995615 - Disclosure - Note 13 - Capital Stock - Outstanding Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 995616 - Disclosure - Note 14 - Net Loss Per Share - Computation of Basic and Diluted Net Income (Loss) Per Share (Details) link:calculationLink link:definitionLink link:presentationLink 995617 - Disclosure - Note 14 - Net Loss Per Share - Antidilutive Securities Excluded from Computation (Details) link:calculationLink link:definitionLink link:presentationLink 995618 - Disclosure - Note 15 - Related Party Transactions (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995619 - Disclosure - Note 15 - Related Party Transactions - Revenue From 4Life Agreement (Details) link:calculationLink link:definitionLink link:presentationLink 995620 - Disclosure - Note 16 - Geographic and Segment Information - Profit and Loss Information by Reportable Segment (Details) link:calculationLink link:definitionLink link:presentationLink 995621 - Disclosure - Note 16 - Geographic and Segment Information - Reconciliation of the Reportable Segments' Loss From Operations to Consolidated (Details) link:calculationLink link:definitionLink link:presentationLink 995622 - Disclosure - Note 16 - Geographic and Segment Information - Assets by Reportable Segment (Details) link:calculationLink link:definitionLink link:presentationLink 995623 - Disclosure - Note 16 - Geographic and Segment Information - Other Items from Segments by Reportable Segment (Details) link:calculationLink link:definitionLink link:presentationLink 995624 - Disclosure - Note 17 - Subsequent Events (Details Textual) link:calculationLink link:definitionLink link:presentationLink